Development of diagnostic tools and Development of therapeutic tools. This research axis aims to identify biomarkers and develop specific inhibitors targeting the bacteria-cell interaction.
  • Development of diagnostic tools.
    • Molecular detection of AIEC bacteria
    • Search for biomarkers to identify AIEC-colonized CD patients
    • Predictive diagnosis of post-operative recurrence in CD patients
    • Colibactin-producing E. coli as a pronostic marker in CRC
  • Development of therapeutic tools
    • Impact of physical activity on microbiota composition in chronic diseases
    • Inhibition of type 1 pili-CEACAM6 interaction
    • Antagonist effects of Probiotics against pathogenic E. coli
    • Eradication of AIEC using antibiotherapy strategies
    • Inhibition of the genotoxic action of the pks genomic island
    • Curcumin as a complementary therapeutic strategy: impact on the intestinal microbiota